G.46 6 (G46) — all aircraft in the radar
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Facts
- In database
- 1 aircraft
- Rarity
- ★★★★★
- Most common operators
- Private
About the type: GR-46611
GR-46611 is a non-selective serotonin 5-HT1 receptor agonist of the triptan group which has been used in scientific research. It is specifically an agonist of the serotonin 5-HT1A, 5-HT1B, and 5-HT1D receptors. The drug's affinities (Ki) are 1.3 nM for the serotonin 5-HT1A receptor, 0.1 to 1.3 nM for the serotonin 5-HT1B receptor, and 0.2 to 1.0 nM for the serotonin 5-HT1D receptor. Conversely, it showed very weak affinity for the serotonin 5-HT2A receptor (Ki = 1,000 nM). The drug does not alter or stimulate locomotor activity when given alone in rodents, but does potentiate the hyperlocomotion induced by the serotonin 5-HT1A receptor agonists 8-OH-DPAT and buspirone. The chemical synthesis of GR-46611 has been described. GR-46611 was first described in the scientific literature by 1994.
Aircraft in the radar
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See all G.46 6 and the surrounding airspace in real time in the spotter radar — get the Aero.Academy app now.